This is the first non-beta release of Kraken 2. This version includes bug fixes and revisions to the build process to aid in making Kraken 2 databases more easily reproducible. Version 2.1.0 also introduces a new experimental feature to report the number of distinct minimizers associated with a taxon in the sequencing data, similar to the functionality found in the KrakenUniq program. Please see CHANGELOG.md for more details on version-specific changes and the operating manual section on "Distinct minimizer count information" to learn how to use the new feature.